Seminars

15 Oct 2008
Lighting up the pathways to cell death: fluorescence microscopy approaches to studying apoptosis

Lisa Bouchier-Hayes, PhD provides an excellent review of apoptosis, or programmed cell death, including the fundamental steps of apoptosis and its importance in cell function. The importance of apoptosis is to sculpt tissues in embryogenesis and metamorphosis, which are primary steps for growth...

Keywords: Apoptosis Confocal Microscopy Cytocrome Cytochrome C-GFP Homeostasis Fluorescent Proteins

15 Oct 2008
The Role of p53 in Retinoblastoma

Retinoblastoma is the third most common form of cancer in infants. Samantha Cicero, PhD, describes the consequences of inactivation of the p53 pathway in retinoblastoma. She begins by describing the demographics and characteristics of retinoblastoma and the landmark discoveries in retinoblastoma...

Keywords: Retinoblastoma P54 Pathway Genetics Cancer Genetics Gene Inactivation P53 P54 MDMX Amplification Apoptosis Xenograft MDM2 Nutlin-3a Topotecan

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