15 Oct 2008

The Role of p53 in Retinoblastoma

by Samantha Cicero, PhD

Retinoblastoma is the third most common form of cancer in infants. Samantha Cicero, PhD, describes the consequences of inactivation of the p53 pathway in retinoblastoma. She begins by describing the demographics and characteristics of retinoblastoma and the landmark discoveries in retinoblastoma...

Keywords: Retinoblastoma P54 Pathway Genetics Cancer Genetics Gene Inactivation P53 P54 MDMX Amplification Apoptosis Xenograft MDM2 Nutlin-3a Topotecan

08 Jun 2010

Genetics and Cancer

by Joy Nakitandwe, PhD, MS

Keywords: Cancer Abnormal Cell Growth School Program Public Education Genetic Mutation Point Mutation LOH Gene Amplification Chromosome Deletion Chromosome Translocation Genetic Instability Cancer Genetics Cancer Genomics